{"id":7637,"date":"2021-01-29T20:27:29","date_gmt":"2021-01-29T20:27:29","guid":{"rendered":"https:\/\/www.adbioink.com\/?post_type=product&p=7637"},"modified":"2023-07-01T20:52:09","modified_gmt":"2023-07-01T19:52:09","slug":"gelma-biyomurekkep","status":"publish","type":"product","link":"https:\/\/www.adbioink.com\/tr\/product\/gelma-biyomurekkep\/","title":{"rendered":"GelMA Biyom\u00fcrekkep"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n
E\u015f anlaml\u0131<\/strong><\/td>\nGelMA biyom\u00fcrekkep, Metakrilatl\u0131 jelatin biyom\u00fcrekkep, Jelatin metakrilat biyom\u00fcrekkep, Jelatin metakriloil biyom\u00fcrekep<\/td>\n<\/tr>\n
Sterilite<\/strong><\/i><\/td>\nSteril<\/td>\n<\/tr>\n
Endotoksin seviyesi<\/strong><\/i><\/td>\n<50 EU\/mL<\/td>\n<\/tr>\n
H\u00fccre canl\u0131l\u0131\u011f\u0131<\/strong><\/i><\/td>\n\u226585% fibroblast, osteoblast and mezenkimal k\u00f6k h\u00fccreler<\/td>\n<\/tr>\n
pH<\/strong><\/td>\n7.3 – 7.4<\/td>\n<\/tr>\n
Metakrilasyon derecesi<\/strong><\/i><\/td>\n>80% (GelMA High)<\/p>\n

50-60% (GelMA Middle)<\/td>\n<\/tr>\n

Form<\/strong><\/td>\nGel<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

AdBioInk Biyosistem Teknoloji taraf\u0131ndan geli\u015ftirilen GelMA\u00a0 biyom\u00fcrekkep \u00fcr\u00fcnleri, iki farkl\u0131 fotoba\u015flat\u0131c\u0131 (Irgacure2959 ve LAP) kullan\u0131larak haz\u0131rland\u0131. NIH-3T3 h\u00fccre hatt\u0131na kar\u015f\u0131 h\u00fccre yap\u0131\u015fmas\u0131 ve h\u00fccre kaps\u00fclleme deneyleri yap\u0131ld\u0131. H\u00fccre canl\u0131l\u0131\u011f\u0131 testlerinde Live\/Dead kiti kullan\u0131ld\u0131. UV veya g\u00f6r\u00fcn\u00fcr \u0131\u015f\u0131k \u00e7apraz ba\u011fl\u0131 ve h\u00fccre kaps\u00fcll\u00fc yap\u0131da h\u00fccre canl\u0131l\u0131klar\u0131n\u0131n %95’in \u00fczerinde oldu\u011fu g\u00f6zlendi.<\/p>\n

\u00c7apraz ba\u011fl\u0131 GelMA biyom\u00fcrekkeplerinin i\u00e7indeki ve \u00fczerindeki h\u00fccre morfolojileri, DAPI-ACTIN boyamas\u0131 ile analiz edildi. GelMA biyom\u00fcrekkeplerine ekilen h\u00fccreler, h\u00fccre morfolojisini 1. g\u00fcnde ald\u0131 ve 7. g\u00fcnde \u00e7o\u011falarak biyom\u00fcrekkep \u00fczerinde %90’\u0131n \u00fczerinde birle\u015fme g\u00f6sterdi. Kaps\u00fcllenmi\u015f h\u00fccreler, 7. g\u00fcnde sitoplazmik \u00e7\u0131k\u0131nt\u0131lar g\u00f6stermeye ba\u015fl\u0131yor gibi g\u00f6r\u00fcnmektedir.<\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

GelMA (jelatin metakrilat), metakrilat gruplar\u0131 i\u00e7eren kollajen t\u00fcrevinin hidroliz \u00fcr\u00fcn\u00fcd\u00fcr. GelMA, h\u00fccre yeniden \u015fekillenmesi i\u00e7in de uygun olan h\u00fccre ba\u011flanmas\u0131n\u0131 destekleyen arginin-glisin-aspartik asit (RGD) dizileri i\u00e7erir. GelMA biyom\u00fcrekkep, h\u00fccresel davran\u0131\u015flar\u0131 kontrol etmek, h\u00fccre-biyomateryal etkile\u015fimlerini incelemek ve dokular\u0131 tasarlamak i\u00e7in ideal platformlar sa\u011flayarak hidrojel mikro fabrikasyonunun benzersiz modeller, morfolojiler ve 3B yap\u0131lar olu\u015fturmas\u0131n\u0131 sa\u011flar. GelMA hidrojellerinin m\u00fckemmel biyouyumlulu\u011fu, onlar\u0131 do\u011fal ECM’yi taklit eden doku iskeleleri olarak uygun hale getirir. S\u0131k\u0131\u015ft\u0131rma mod\u00fclleri, metakrilasyon derecesinin derecesi de\u011fi\u015ftirilerek ayarlan\u0131r ve bu da onu \u00e7ok \u00e7e\u015fitli biyomedikal uygulamalar i\u00e7in uygun GelMA biyom\u00fcrekkep haline getirir.<\/p>\n

Ayr\u0131ca GelMA, biyom\u00fcrekkep uygulamalar\u0131 i\u00e7in iyi bir aday olabilir. 3D bask\u0131l\u0131 GelMA iskeleleri, m\u00fckemmel h\u00fccre canl\u0131l\u0131\u011f\u0131na ve iskele stabilitesine sahiptir. Nanoteknoloji ve GelMA hidrojellerinin kombinasyonu, doku m\u00fchendisli\u011finde umut verici faydalar sa\u011flayacakt\u0131r.<\/p>\n

Adbioink protokollerimizi takip ederek ki\u015fiselle\u015ftirilmi\u015f bioinkler olu\u015fturmak kolayd\u0131r.<\/p>\n

Dok\u00fcmanlar<\/h2>\n