{"id":8088,"date":"2021-10-10T14:47:16","date_gmt":"2021-10-10T13:47:16","guid":{"rendered":"https:\/\/www.adbioink.com\/?post_type=product&p=8088"},"modified":"2025-05-25T08:56:31","modified_gmt":"2025-05-25T07:56:31","slug":"kappa-karagenan-biyomurekkep","status":"publish","type":"product","link":"https:\/\/www.adbioink.com\/tr\/product\/kappa-karagenan-biyomurekkep\/","title":{"rendered":"Kappa Karagenan Biyom\u00fcrekkep"},"content":{"rendered":"

Sterilite\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/strong>Steril<\/p>\n\n\n\n\n\n\n\n
E\u015f anlaml\u0131<\/strong><\/td>\nKapMA Biyom\u00fcrekkep, Metakrilat Kappa Karagenan Biyom\u00fcrekkep<\/td>\n<\/tr>\n
Endotoksin seviyesi<\/strong><\/i><\/td>\n<50 EU\/mL<\/td>\n<\/tr>\n
H\u00fccre canl\u0131l\u0131\u011f\u0131<\/i><\/b><\/td>\n\u226585% mezenkimal k\u00f6k h\u00fccreler ve osteoblast h\u00fccreleri<\/td>\n<\/tr>\n
pH<\/strong><\/td>\n7.3 – 7.4<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nJel<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/div>\n
\n

Kappa karagenan biyom\u00fcrekkep (KapMA), AdBioink taraf\u0131ndan geli\u015ftirildi ve fibroblast h\u00fccresi NIH 3T3 ile h\u00fccre deneyleri yap\u0131ld\u0131. UV ve g\u00f6r\u00fcn\u00fcr \u0131\u015f\u0131k ile 2 farkl\u0131 \u015fekilde foto-\u00e7apraz ba\u011flanan Kappa karagenan biyom\u00fcrekkeplerinin h\u00fccre adezyonu ve kaps\u00fclleme deneyleri ger\u00e7ekle\u015ftirildi. H\u00fccre morfolojileri 1. ve 7. g\u00fcnlerde DAPI-ACTIN boyamas\u0131 ile incelendi. Kappa karagenan biyom\u00fcrekkeplerine yap\u0131\u015fan h\u00fccreler \u00e7o\u011fald\u0131 ve h\u00fccre morfolojilerini koruyabildi. Kaps\u00fcll\u00fc h\u00fccrelerin 7. g\u00fcnde sitoplazmik uzant\u0131lar olu\u015fturmaya ba\u015flad\u0131\u011f\u0131 g\u00f6r\u00fcld\u00fc. H\u00fccre canl\u0131l\u0131\u011f\u0131n\u0131n incelendi\u011fi Live\/Dead boyama sonu\u00e7lar\u0131na g\u00f6re h\u00fccre canl\u0131l\u0131\u011f\u0131n\u0131n %95’in \u00fczerinde oldu\u011fu ve kaps\u00fcllenmi\u015f h\u00fccrelerin canl\u0131l\u0131\u011f\u0131n\u0131 7 g\u00fcn boyunca korudu\u011fu g\u00f6r\u00fcld\u00fc.<\/strong><\/p>\n<\/div>\n

\"\"
KapMA Bioink Cell Adhesion, KapMA Bioink Cell Viability, KapMA Bioink Cell Morphology, Adbioink, Bioink<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

Kappa karagenan biyom\u00fcrekkebi, 3B biyobask\u0131 i\u00e7in ticarile\u015ftirilmi\u015f ilk kappa karagenan biyom\u00fcrekkebidir. Karagenan, alglerden ekstrakte edilen hidrofilik bir polimerdir ve jelle\u015ftirme maddesi ve em\u00fclsifiye edici madde olarak kullan\u0131l\u0131r. Farkl\u0131 karagenan t\u00fcrleri aras\u0131nda, disakkarit ba\u015f\u0131na bir s\u00fclfatlanm\u0131\u015f grup (%25 ila 30 ester s\u00fclfat i\u00e7eri\u011fi) i\u00e7eren, do\u011fal, do\u011frusal suda \u00e7\u00f6z\u00fcn\u00fcr bir polisakkarit olan Kappa karagenan (\u03baCA), doku m\u00fchendisli\u011finde uygun biyomateryallerden biridir. Kappa karagenan biyom\u00fcrekkebi, jelle\u015fme \u00f6zellikleri, mekanik dayan\u0131kl\u0131l\u0131\u011f\u0131 ve do\u011fal h\u00fccre d\u0131\u015f\u0131 matrislerin (ECM) ana bile\u015fenleri olan kondroitin-4-s\u00fclfat ve dermatan s\u00fclfata benzerli\u011fi nedeniyle enjekte edilebilir formda bu alan i\u00e7in potansiyel bir aday olarak g\u00f6r\u00fclm\u00fc\u015ft\u00fcr.<\/p>\n

Kappa karagenan biyom\u00fcrekkebi, tiksotropik bir polimerdir ve iyonik \u00e7apraz ba\u011flama y\u00f6ntemiyle hidrojel formuna d\u00f6n\u00fc\u015ft\u00fcr\u00fclebilir. Bununla birlikte, bu \u00e7apraz ba\u011flama y\u00f6ntemleri, fizyolojik ko\u015fullarda d\u00fc\u015f\u00fck stabiliteye sahip olan hidrojelleri sunar. Bu dezavantaj\u0131n \u00fcstesinden gelmek i\u00e7in Kappa karagenan metakrilatlanarak (KapMA) fotopolimerizasyon potansiyeline sahip KapMA sentezlenir.<\/p>\n

Kappa karagenan biyom\u00fcrekkep, konsantrasyona, s\u0131cakl\u0131\u011fa, iyonlar\u0131n varl\u0131\u011f\u0131na ve molek\u00fcler a\u011f\u0131rl\u0131\u011fa ba\u011fl\u0131 olarak ayarlanabilir bir viskozite \u00f6zelli\u011fine sahiptir ve y\u00fcksek mukavemet, toksik olmayan ve h\u00fccresel uyumluluk \u00f6zelliklerine sahiptir. Kesmeyle incelme ve \u0131s\u0131yla tersine \u00e7evrilebilir \u00f6zellikleri biyom\u00fcrekkepler i\u00e7in uygun oldu\u011fundan, Kappa-karagenan 3B ekstr\u00fczyon tabanl\u0131 biyobask\u0131 i\u00e7in bir biyom\u00fcrekkep malzemesi olarak se\u00e7ilebilir.<\/p>\n","protected":false},"featured_media":8113,"comment_status":"open","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"product_cat":[19,311],"product_tag":[32,34,113,126,128,129],"yoast_head":"\nKappa Karagenan Biyom\u00fcrekkep - Adbioink\/tr<\/title>\n<meta name=\"description\" content=\"Kappa karagenan biyom\u00fcrekkep \u00fcr\u00fcn\u00fc, 3B biyobask\u0131 i\u00e7in ticarile\u015ftirilmi\u015f ilk kappa karagenan biyom\u00fcrekkebidir. 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